科研项目

2012.1-2015.12，国家自然科学基金青年项目

2014.1-2015.6，北京市自然科学基金预探索项

2014.1-2017.12，国家重大新药创制子课

2016.1-2019.12，国家自然科学基金面上项目

2018.1-2020.12，北京市自然科学基金面上项目

2020.1-2023.12，国家自然科学基金联合基金重点项目

2021.1-2023.12，国家自然科学基金优秀青年基金项目

著作论文

[1] Zhou, Kaixiang; Yuan, Chang; Dai, Bin; Wang, Kan; Chen, Yimin; Ma, Denglei; Dai, Jiapei; Liang, Yi*; Tan, Hongwei*; Cui, Mengchao*, Environment-Sensitive Based Near-Infrared Probe for Fluorescent Discrimination of Aβ and Tau Fibrils in AD Brain, J. Med. Chem., 2019, 62(14): 6694-6704

[2] Zhang, Xiaoyang; Hou, Yaqin; Peng, Cheng; Wang, Chu; Wang, Xiang; Liang, Zhigang*; Lu, Jing; Chen, Baian*; Dai, Jiapei; Liu, Boli; Cui, Mengchao*, Oligoethyleneoxy-Modified 99mTc-Labeled β‑Amyloid Imaging Probes with Improved Brain Pharmacokinetics for Single-Photon Emission Computed Tomography, J. Med. Chem., 2018, 61(3): 1330-1339

[3] Fu, Hualong; Cui, Mengchao*; Zhao, Liu; Tu, Peiyu; Zhou, Kaixiang; Dai, Jiapei; Liu, Boli, Highly Sensitive Near-Infrared Fluorophores for in Vivo Detection of Amyloid-beta Plaques in Alzheimer's Disease, J. Med. Chem., 2015, 58(17): 6972-6983

[4] Yang, Yanping; Cui, Mengchao*; Zhang, Xiaoyang; Dai, Jiapei; Zhang, Zhiyong; Lin, Chunping; Guo, Yuzhi; Liu, Boli, Radioiodinated Benzyloxybenzene Derivatives: A Class of Flexible Ligands Target to β-Amyloid Plaques in Alzheimer's Brains, J. Med. Chem., 2014, 57(14): 6030-6042

[5] Li, Zijing; Cui, Mengchao*; Dai, Jiapei; Wang, Xuedan; Yu, Pingrong; Yang, Yanping; Jia, Jianhua; Fu, Hualong; Ono, Masahiro; Jia, Hongmei; Saji, Hideo; Liu, Boli*, Novel Cyclopentadienyl Tricarbonyl Complexes of Tc-99m Mimicking Chalcone as Potential Single-Photon Emission Computed Tomography Imaging Probes for β-Amyloid Plaques in Brain, J. Med. Chem., 2013, 56(2): 471-482

[6] Cui, Mengchao; Ono, Masahiro*; Kimura, Hiroyuki; Ueda, Masashi; Nakamoto, Yuji; Togashi, Kaori; Okamoto, Yoko; Ihara, Masafumi; Takahashi, Ryosuke; Liu, Boli; Saji, Hideo, Novel F-18-Labeled Benzoxazole Derivatives as Potential Positron Emission Tomography Probes for Imaging of Cerebral β-Amyloid Plaques in Alzheimer's Disease, J. Med. Chem., 2012, 55(21): 9136-9145

[7] Cui, Mengchao*; Wang, Xuedan; Yu, Pingrong; Zhang, Jinming; Li, Zijing; Zhang, Xiaojun; Yang, Yanping; Ono, Masahiro; Jia, Hongmei; Saji, Hideo; Liu, Boli*, Synthesis and Evaluation of Novel F-18 Labeled 2-Pyridinylbenzoxazole and 2-Pyridinylbenzothiazole Derivatives as Ligands for Positron Emission Tomography (PET) Imaging of β-Amyloid Plaques, J. Med. Chem., 2012, 55(21): 9283-9296. (Cover Article)

[8] Cui, Mengchao; Ono, Masahiro*; Kimura, Hiroyuki; Liu, Boli; Saji, Hideo*, Synthesis and Structure-Affinity Relationships of Novel Dibenzylideneacetone Derivatives as Probes for β-Amyloid Plaques, J. Med. Chem., 2011, 54(7): 2225-2240