詹婷洁，广东广州人，环境科学博士，现任北京师范大学文理学院生物系讲师、硕士生导师。2017年本科毕业于中国药科大学，2022年获浙江大学环境科学博士学位，随后于美国罗格斯大学药理学院从事博士后研究工作。主要研究方向为雌性生殖健康与毒理学，解析环境因素及药物等分子对女性生殖健康的干扰机制。在《Environmental Health Perspective》、《Environmental Science & Technology》等期刊以第一作者或合作作者身份发表论文23篇。现主持国家自然科学基金青年科学基金项目。曾以报告人身份参加国际毒理大会等国内外学术会议8次，并获得相关荣誉奖励8项。

教育背景

2013.09-2017.06    中国药科大学，环境科学，理学学士

2017.09-2022.06    浙江大学，环境科学，工学博士

工作经历

2022-2025：罗格斯大学（Rutgers University, Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy），博士后，研究方向：雌性生殖健康与毒理学

研究方向

（1） 雌性生殖健康与生殖毒理机制

（2） 雌性生殖系统模型的建立与优化

（3） 外源分子的生物转化及其介导的毒性变化

科研项目

1. 国家自然科学基金委员会青年项目C类；基于3D卵泡模型与高分辨组学的生殖毒物机制解析与组分识别；2026-2028；主持

发表论文

1) Pawat Pattarawat*, Tingjie Zhan*, Yihan Fan, Jiyang Zhang, Hilly Yang, Ying Zhang, Sarahna Moyd,, Nataki C. Douglas, Margrit Urbanek, Brian Buckley, Joanna Burdette, Qiang Zhang, Ji-Yong Julie Kim, Shuo Xiao, Ovarian disrupting effects and mechanisms of long- and short-chain perand polyfluoroalkyl substances in mice, Environmental Health Perspectives , 2025. 

2) Tingjie Zhan, Lilai Shen, Yuyao Zhang, Fang Wan, Yu Qiu, Qinyang Jin, Yiqu Wu, Yizhou Huang, Shulin Zhuang, Decidual Disrupting Effects of Low-Dose Benzophenone-Type UV Filters in Human Endometrial Stromal Cells via ER/PR/FOXO1 Signaling, Environmental Science & Technology , 2025, 59(13):6464-6476. 

3) Tingjie Zhan, Liumeng Pan, Zhenfeng Liu, Jiayan Chen, Zhi-Wei Ge, Liping Lu, Xiaofang Zhang, Shixuan Cui, Chunlong Zhang, Weiping Liu, Shulin Zhuang*. Metabolic susceptibility of 2-chlorothioxanthone and its toxic effects on mRNA and protein expression and activities of human CYP1A2 and CYP3A4 enzymes.   Environmental Science & Technology , 2018, 52: 11904-11912. 

4) Tingjie Zhan, Ying Zhang, Qingshi Zhao, Anat Chemerinski, Nataki Douglas, Qiang Zhang*, and Shuo Xiao*. A dose-response study on functional and transcriptomic effects of FSH on ex vivo mouse folliculogenesis.  Endocrinology , 2024, 27,165(7), bqae054. 

5) Tingjie Zhan, Shixuan Cui, Huafeng Shou, Leilei Gao, Shaoyong Lu, Chunlong Zhang, Shulin Zhuang*. Transcriptome aberration in mice uterus associated with steroid hormone response and inflammation induced by dioxybenzone and its metabolites. Environmental Pollut ion , 2021, 286, 117294.

6) Tingjie Zhan, Leili Zhang, Shixuan Cui, Weiping Liu, Ruhong Zhou, Shulin Zhuang*. Dioxybenzone triggers enhanced estrogenic effect via metabolic activation: in silico and in vitro investigation. Environmental Pollution , 2021, 268, 115766.

7) Tingjie Zhan, Shixuan Cui, Xujun Liu, Chunlong Zhang, Yu-ming Huang*, Shulin Zhuang*. Enhanced Disrupting Effect of Benzophenone-1 Chlorination Byproducts to Androgen Receptor: Cell-based Assays and Gaussian Accelerated Molecular Dynamics Simulations. Chemical Research in Toxicology , 2021, 34:1140–1149.

8) Yuyao Zhang*, Tingjie Zhan, Yang Sun, Lun Lu, Baoliang Chen. Revolutionizing solid-state NASICON sodium batteries: Enhanced ionic conductivity estimation through multivariate experimental parameters leveraging machine learning. ChemSusChem , 2023, e202301284.

9) Xujun Liu, Tingjie Zhan, Yuchen Gao, Shixuan Cui, Weiping Liu, Chunlong Zhang, Shulin Zhuang*. Benzophenone-1 induced aberrant proliferation and metastasis of ovarian cancer cells via activated ERα and Wnt/β-catenin signaling pathways. Environmental Pollut ion , 2022, 292, 118370.

10) Hao Wu, Tingjie Zhan, Shixuan Cui, Jiaya Chen, Qinyang Jin, Weiping Liu, Chunlong Zhang*, Shulin Zhuang*. Endothelial barrier dysfunction induced by anthracene and its nitrated or oxygenated derivatives at environmentally relevant levels. Science of The Total Environment , 2022, 802,149793.

11) Liping Lu, Tingjie Zhan, Mei Ma, Chao Xu, Jingpeng Wang, Chunlong Zhang, Weiping Liu, Shulin Zhuang*. Thyroid disruption by bisphenol S analogues via thyroid hormone receptor β: in vitro, in vivo and molecular dynamics simulation study. Environmental Science & Technology , 2018, 52: 6617-6625.

教学工作

本科生：《生物化学》、《微生物学实验》

荣誉获奖

1.2023年：The Reproductive and Developmental Toxicology Specialty Section (RDTSS) Poster Award in 2023 SOT conference（美国纳什维尔）

2.2019年：第十届全国环境化学大会（中国天津） 分会优秀展报奖

3.2019年：第15届国际毒理学大会（美国夏威夷） SOT Endowment Fund Travel Award